Series of Synthons

Activate Scientific, upon customers´ request, develops Series of Synthons which have the same core structure but various functional groups. Our chemistry expertise is within smaller complex, fused Heterocyclic Ring systems, carrying various substituents and multiple functional groups at diffcult ring positions.

Please call on us for your specific Custom development project.

Examples of developed Series of Synthons, up to 50g quantities

Ethyl 5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate HCl
7-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylic acid
tert-butyl 3-Bromo-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate
tert-butyl 5,6-Dihydro-3-methoxy-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate
2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine HCl
3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine HCl
2,4-Dichloro-1,8-naphthyridine
Ethyl 4-chloro-1,8-naphthyridine-3-carboxylate
2-Amino-5-formylthiazole
2-Bromo-5-thiazolecarboxylic acid
2-Amino-4-chloro-5-formylthiazole
4-Bromo-2-isopropylthiazole
2-Fluoropyridine-3-boronic acid
2-Fluoropyridine-4-boronic acid
2-Fluoro-5-(tributylstannyl)pyridine

Activate Scientific is a fully equipped service provider of Heterocyclic Custom Building Blocks for research projects in preclinical development

  • Series of heterocyclic Synthons, 5-50g
  • Multistep Custom Synthesis, 7-8 steps up to 5-10g
  • Exclusive Blocks ™, 5-10g
  • Heterocyclic Custom chemicals, up to 1-2kg
  • Fine Intermediates, Production of Fine heterocyclic Intermediates for pilot plant development

We provide very competitive pricing.

Custom made compounds are usually delivered within three to four weeks if it is a two- or three-step synthesis and in one kilogram quantity or less. For more information, call us at +49-(0)941-2902411, or send an email to rschmitt@activate-scientific.com.

Chemistry Services for Drug Discovery
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