Welcome to Activate Scientific GmbH

The business of Activate Scientific is the production and distribution of Novel Reactive Intermediates, Exclusive Building Blocks (Exclusive Blocks ™) and Series of Synthons for Drug Discovery. We are the partner for the distribution and promotion of Synthonix Inc. (USA) products in Europe.

Our Business is Pre-Pack!
We do carry 80% of the listed products in stock.

World‘s Largest Collection of Novel Scaffolds

We have considerably expanded our catalogue of scaffolds for Medicinal Chemistry. The catalogue contains over 2000 rigid heterocyclic based fused ring systems which are very powerful synthetic tools. These small and multifunctional compounds are versatile templates to allow the rapid exploration of chemical space making them ideal for early hit identification, fragment based approaches, hit-to-lead programmes, library production and scaffold hopping. The availability of region-isomers within related templates allows the swift access to SAR and the inclusion of heteroatoms aids the modification of physicochemical properties and probes binding sites. The incorporation of protection groups and synthetically tractable functional groups such as aryl halides enables expedient synthetic strategies. Our compounds are in stock for express delivery at competitive prices. Custom synthesis of proprietary scaffolds is available on request. Please examine a sample selection of the variety of scaffolds available on this page.

To view the complete list of our scaffolds, accurate availability and pricing information, please check by Fused Rings

• 2-Amino-5-cyanopyrrolo[2,3-d]pyrimidine-4-one 95+%
• 3-Bromopyrazolo[1,5-a]pyrimidin-7-amine 95+%
• 4-Amino-2-(methylthio)pyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile 95+%

• 5-Bromo-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid 95+%
• 3-Bromo-7-(trifluoromethyl)imidazo[1,2-a]pyrimidine 98%
• Ethyl 5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate HCl 95+%

• cis-5-Boc-1H-Hexahydropyrrolo[3,4-b]pyrrole 97%
• 6-Chloroimidazo[1,2-b]pyridazine-3-carbaldehyde 95%
• 2-Bromo-7-iodo-5H-pyrrolo[2,3-b]pyrazine 95+%

• 5-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine 95+%
• 1,4-Dichloropyrido[4,3-d]pyridazine 95+%
• 4-Aminopyrimido[4,5-d]pyrimidine 97%

• 2-Bromo-4-chlorothieno[3,2-c]pyridine 95+%
• 6-Bromoimidazo[1,2-a]pyrazin-8-amine 95+%
• 3-Bromo-4H-thieno[3,2-b]pyrrole-5-carboxylic acid 95+%

• 6-Bromooxazolo[4,5-b]pyridin-2(3H)-one 97%
• tert-butyl 2,4-Dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate 95+%
• tert-butyl 3-Amino-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate 95+%

• Ethyl 5-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate 95+%
• 4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine 95+%
• 2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine TFA 95+%

• tert-butyl 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate 95+%
• 3-Bromo-4-chloro-1H-pyrrolo[3,2-c]pyridine 95+%
• 2,4-Dichlorofuro[3,2-d]pyrimidine 95+%

• 6-Chloropyrimido[5,4-d]pyrimidin-4(3H)-one 95+%
• tert-butyl 3-Bromo-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate 95+%
• 3-(2-Bromoimidazo[2,1-b]thiazol-6-yl)propanoic acid HCl 95+%

• 4-Chlorothieno[3,2-d]pyrimidine-6-carboxylic acid 95+%
• 7-Bromofuro[3,2-c]pyridin-4(5H)-one 95+%
• 6-Bromopyrrolo[1,2-f][1,2,4]triazin-4(3H)-one 95+%

• 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole dihydrochloride 95+%
• 6-Chloropyrido[2,3-b]pyrazine 95+%
• 4-Chloro-2-iodo-1H-pyrrolo[2,3-b]pyridine 95+%